Supplementary data for:
Anna Oberle, Franziska Hanzer, Felix Kokocinski, Anna Ennemoser, Luca Carli, Enrico Vaccari, Markus Hengstschläger, Michael Feichtinger
Evaluation of nanopore sequencing on polar bodies for routine pre-implantation genetic testing for aneuploidy
The raw data (binned read counts of all samples used) can be accessed here.
The format of the files is explained in the following table:
Column | Meaning | Example value |
chrom | Region coordinates: Chromosome | chr1 |
start | Region coordinates: Start of the bin | 3000000 |
end | Region coordinates: End of the bin | 3500000 |
cn_change | Automatically detected copy-number change | 0 |
genomic_mid | Region coordinates: Midpoint of the bin as a genome-wide coordinate | 3250000 |
raw_counts | Read number overlapping bin | 0 |
counts | Read number adjusted by in-silico reference | 3.804 |
median | Read number after median-normalization | 2.961 |
shrinker | Read number after adjusted with region median | 3.55109992 |
counts_smooth | Read number after smoothing window | 3.33059988 |
percentcounts | Read number as percentage of total reads | 0.0688 |